PKRRATING THINGS TO KNOW BEFORE YOU BUY

3B). R526 with the loop among αJ and αI anchors the C-terminal part of the activation loop by forming a salt bridge with E458 at the base of αEF. Q459 stabilizes the HRD motif by a hydrogen bond to the leading chain carbonyl of R413. The tip on the activation section is stabilized by check here a hydrogen bond between Y454 and E480 from αF. whi